Combination therapy for pain in musculoskeletal diseases

ASICs Mediate Pain and Inflammation in Musculoskeletal Diseases.

Chronic musculoskeletal pain is debilitating and affects ∼ 20% of adults. Tissue acidosis is present in painful musculoskeletal diseases like rheumatoid arthritis. ASICs are located on skeletal muscle and joint nociceptors as well as on nonneuronal cells in the muscles and joints, where they mediate nociception. This review discusses the properties of different types of ASICs, factors affecting...

Therapeutic Ultrasound and Pain in Degenerative Diseases of Musculoskeletal System

INTRODUCTION Therapeutic ultrasound is a physical modality which is constantly expanding range of indications. Analgesic effect of ultrasound is still under discussion. Regardless the extensive application of pulsed ultrasound of low intensity, continuous ultrasound has a better analgesis effect, which is explained by its mechanism of action. AIMS The main research objective of this study was...

The Fear of Movement/Pain in Musculoskeletal Pain-A Review

Objective: To investigate and review psychological influences of pain such as kinesiophobia and pain-related fear on patients with musculoskeletal pain and on rehabilitation outcomes. Materials & Methods: Fear is a universal and powerful emotion and, as a result, it can have a profound impact on human behavior. the fear-motivated behavior has the potential to adversely impact rehabilitation ...

Musculoskeletal ultrasound-guided physical therapy in hemiplegic shoulder pain

RATIONALE The use of musculoskeletal ultrasound (MU) method in the diagnosis of shoulder pain and injury and guidance of injection and pain blocking has been established. However, the treatment of posthemiplegic shoulder pain (HSP) with MU-guided precise physical therapy has not been reported. PATIENT CONCERNS Here, we present the first case report of a 64-year-old man with a right basal gang...

Pain relief in osteoarthritis: the rationale for combination therapy.